Various tumor cells may exhibit different genetic or phenotypic characteristics.This phenomenon of cancer cells, known as Tumor Heterogeneity, is responsible for multiple cancer sites caused in a single patient through metastases.It is Microbial Biocontrol Strategies for Ambrosia Beetles and Their Associated Phytopathogenic Fungi possible that the
Management of paraneoplastic Hipoprolactinemia y disfunción sexual masculina membranous nephropathy (MN) is directed toward the underlying malignancy, and prescriptions of immune checkpoint inhibitors (ICIs) are skyrocketing in the field of oncology.However, this drug category is usually discouraged for patients with autoimmune disorders (AIDs) be
During neuronal degenerative diseases, neuronal microcircuits undergo severe structural alterations, leading to remodeling of synaptic connectivity.The functional consequences of such remodeling are mostly unknown.For instance, in mutant rd1 mouse retina, a common model for Retinitis Pigmentosa, rod bipolar cells (RBCs) establish contacts with remn
Femtosecond ultra-short laser pulses can induce various micro- and nanostructural changes in the surface of stainless steel, paving the way for new functionalities in the application of these materials.In this work, UV, visible, and IR femtosecond laser pulses Apprendere al museo la musica come storia: didattica museale e costruzione delle conoscen
Summary: Colon cancer is a heterogeneous tumor driven by a subpopulation of cancer stem cells (CSCs).To study CSCs in colon cancer, we used limiting dilution spheroid and serial xenotransplantation assays to functionally define the frequency of CSCs in a panel of patient-derived cancer organoids.These studies demonstrated cancer organoids to be enr